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Eluxadoline is a medication used for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. The most common side effects of eluxadoline are mild constipation, nausea, and abdominal pain. There are important safety considerations for eluxadoline including rare but serious side effects and a potential for drug-drug interactions.
Gasoline and diesel are petroleum hydrocarbons. Inhaling their fumes can cause lung irritation and neurological toxicity. Chronic abuse can be dangerous. Swallowing gasoline/diesel can irritate the digestive tract and result in aspiration into the lungs, resulting in chemical pneumonitis. Skin exposure can cause irritation and redness, while prolonged exposure results in chemical burns.
Fumes from heated metal and burning plastic products can cause flu-like illnesses in people and animals. People who weld metals at work are at risk, as are those who overheat PTFE (Teflon)-coated cookware. Getting away from the source of the fumes is the most important treatment.
5-HTP, which comes from tryptophan found in our diet, is the precursor of serotonin. It is available as a supplement and has appealed to researchers and the public for the treatment of depression, anxiety, insomnia, and a wide range of other conditions. To date, evidence of its effectiveness has been inconclusive and there are important safety concerns.
Soaps are anionic surfactants used for washing and cleaning. Swallowing a small amount of soap is usually not harmful. It can irritate the mouth and throat and cause mild gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Some people may be allergic to some of the ingredients in soap, which can result in difficulty breathing, skin irritation and rashes.
Angiotensin-converting enzyme inhibitors (ACE-inhibitors) are safe and effective medications used to treat and prevent many cardiovascular conditions. Angioedema, a rare but serious complication, may occur in some people who take ACE inhibitors.
Unintentionally swallowing a few match tips is not dangerous but would be expected to cause some minor irritation to the mouth and stomach. Swallowing a large number of matches can cause serious effects including damage to red blood cells and organs such as the kidneys and liver.
When human skin is exposed to ultraviolet light and certain natural plant-derived substances, a skin condition called “phytophotodermatitis” can occur. This condition is frequently reported after skin exposure to the combination of sunlight and lime juice, and can include skin rashes, blistering, and dark pigmentation. Although it may be painful, phytophotodermatitis generally resolves on its own over time.
Chlorine dioxide and sodium chlorite are highly reactive disinfectants used to treat public water systems. They are also low-concentration ingredients in some mouthwash products. A sip is unlikely to cause anything beyond mild irritation, nausea, and short-term vomiting. Large amounts can oxidize red blood cells, making them incapable of carrying oxygen.
Black widow spider bites can be dangerous but fatal bites are rare. Black widow spider bites often are painful right away. After a bad bite, severe pain and muscle cramps can start in a couple of hours. Pain and muscle cramps can be treated. Antivenin is available but is needed only rarely.
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