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Babies and Ranitidine (Zantac®)

If you are treating your newborn baby with ranitidine (Zantac®) for heartburn, you are not alone. In fact, gastroesophageal reflux (GER), also called heartburn, acid reflux or indigestion, is extremely common in infants and children. As many as 70% of infants vomit at least once every day in their first four months of life due to GER. 

GER occurs when stomach acid backs up into the esophagus, the food pipe that connects the throat to the stomach. Because the esophagus is sensitive and not as thick as the stomach, acid in the esophagus causes pain. Infants with GER may have vomiting, irritability because of the pain, trouble feeding and a cough that does not go away.  

GER often goes away on its own by the time a child is six months old. Until then, doctors often prescribe ranitidine to help relieve the pain and discomfort caused by GER. Ranitidine works by reducing the acid in the stomach. It is given to infants and children in syrup form, though it is also available as tablets. 

The prescribed dosing for ranitidine syrup can be confusing. Many parents make mistakes in dosing their children. For instance, a common mistake is to give 7 milliliters instead of the prescribed 0.7 milliliters. This is ten times the dose ordered by the doctor. 

When parents realize the mistake, they call the poison center in a panic. Poison center experts tell them that ranitidine is safe and well-tolerated. In an overdose, it may cause mild drowsiness. Some children may also have short-term nausea, vomiting and diarrhea. Severe or life-threatening symptoms are very rare. 

Prevent mistakes with ranitidine (and other medicines):

  • Have a routine for who gives a child medicine and when.

  • Use a checklist, schedule, or calendar to note when a child is given medicine.

  • Read the label carefully for the right dose – every time you give medicine.

  • Use measuring syringes for medicines. Get them from your doctor or pharmacy. DO NOT use household spoons and cups to measure medicine doses.

If a child gets too much ranitidine, call the poison center right away at 1-800-222-1222. Bring the package to the phone. The nurse or pharmacist who answers your call will want to know the strength of the medicine and the prescribed dose. 

The poison center will tell you what symptoms to watch for. Usually, no treatment is needed. But, if you need to do anything, the poison center expert will tell you. And, the poison center will stay in touch with you by phone.   

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August 2012, The Poison Post®    
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