Medical Toxicology Fellowship
University of the Health Sciences (USU)
The head of the Division
of Clinical Pharmacology/Medical Toxicology USU is jointly appointed
within the Departments of Medicine and Pharmacology and teaches in both
departments. Ongoing collaborative research and teaching opportunities will
be available to fellows during the 2 months per year they will spend at USU. Fellows will audit the Medical Pharmacology Course
in the Medical School to review this material.
Clinical Research Unit
in the Division of Clinical Pharmacology and Medical
Toxicology, USU, holds a monthly conference covering a variety of topics
related to clinical research, such as ethics, informed consent, assessment
of adverse study events, assignment of causality, Good Clinical Practices
and practical research management issues. The USU faculty in Clinical
Pharmacology/Medical Toxicology will lead the discussion and coordinate the
presentation of material to the group.
The USU Clinical Pharmacology and Toxicology Seminar Series is held weekly
throughout the academic year. Fellows will attend all seminars while on this rotation and, if their research project involves a USU
project, they will present their research to the USU faculty before the
conclusion of their program. They will also learn pharmacokinetics from a
6-hour on-site conference designed for the visiting Fellows.
Clinical rounds on the Clinical Pharmacology Research Unit occur
weekly and include physicians, nurses and fellows in training. During these
rounds, protocol related issues, adverse events, assignment
of causality of adverse events and practical research protocol management
issues are discussed. Fellows will take an active role in presentation of
adverse events during these sessions.
Daily rounds occur on inpatients followed by the Consultation Service
at USU. When patients are on-service, fellows will round on patients
before and with the attending physician to discuss management issues and
provide teaching to the house staff and medical students involved in the
care of the patient.
Experimental design and statistical analysis are taught by attendance in two
courses on study design offered by NIH/Foundation for Advanced Education in
the Sciences. These principles are reinforced at the Research Meeting and
during Journal Club and other conferences. They are discussed in-depth
during the preparation of research proposals for submission to the IRB,
IACUC and grant funding agencies as well as during data analysis and
Laboratory techniques, both research and analytical will be taught during
interactions with the toxicology laboratory during the Fellows’ experience
at USU. They will learn how GC-MS, liquid chromatography and simple
immunoassay toxicology screens are run. Laboratory techniques will also be
reviewed when needed for research or patient care (during rounds).